Along with the deepening and reform of piano teaching, piano teaching resources have been optimized and integrated. The application of Internet technology provides a new opportunity for piano teaching mode and talents training in colleges and universities. Mooc teaching breaks the traditional teaching mode of group class and collective class, and flipped classroom can expand the piano subject practice. Based on the network technology, this study explores the application of the teaching mode of Mooc-based flipped classroom in the teaching reform of piano course. The results show that the teaching method of Mooc improves the ability of resources sharing, liberalization and teaching according to students’ aptitude of piano teaching. The production of Mooc-based flipped classroom makes Internet knowledge and the dissemination of teaching break spacetime limit. Mooc platform is easier for students to apply their abilities to practical application. This study provides idea and platform for the combination of piano teaching and Internet in colleges and universities.