Deepening the open experiment teaching after class is an effective way to improve the quality of experimental teaching and cultivate students’ ability of innovation and entrepreneurship. The empirical research on the open experimental teaching of media undergraduate majors shows that the training focusing on the improvement of professional cognitive ability, practical ability, innovation ability and communication ability has the most obvious effect on the improvement of students’ professional skills and innovation and entrepreneurship ability. In addition, the establishment of evaluation mechanism of different experimental training projects is also an important step to guarantee the quality of training. Therefore, the extra-curricular open experimental teaching project based on the technological development of the media industry will play a positive role in promoting the cultivation of students’ innovation and entrepreneurship ability and improving the in-class experimental teaching system..