Multi-party cooperative education is one of the important contents in the construction of new engineering, and also an effective way to improve the quality of higher engineering education. By using the methods of literature analysis and case study, this study analyzes the defects of the traditional education mode in colleges and universities, and introduces the multi-party cooperative education mode which meets the requirements of new engineering and covers “family-school-internship unit-society”. Then this study puts forward the concrete implementation way of multi-party cooperative education mode in engineering education, namely, to strengthen the psychological quality and gratitude consciousness of college students through family emotion education, to teach the basic knowledge and professional ability to college students through school professional education, to train the practical skills and innovative consciousness of college students through the internship unit, and to promote college students to further understand and fulfil social and professional responsibilities through the social environment. Through three-year application practice test, it is found that the research has played a positive role in training innovative advanced engineering talents and promoting the further development of new engineer education.