Scientific cognition of the brain helps students improve their design thinking abilities. This paper attempts to study the application of the right-brain development philosophy in the architectural design teaching. By using the literature analysis, case analysis and comparative analysis methods, based on the theoretical research results of brain-science-based education and right-brain thinking development at home and abroad, this paper analyzes the specific relationship between the right-brain thinking and the architecture design, and considering the issues in the current architectural design discipline, it constructs a theoretical teaching framework based on the rightbrain development philosophy, designs a teaching program based on right-brain thinking according to the course content of architectural design. Then this paper compares and analyze the teaching effects in actual teaching activities, hoping to provide some new reference and basis for architectural design teaching.