The human’s right brain is the centre of image thinking. It determines human creativity and imagination. In the current teaching of architectural design, the outstanding problem for students is the lack of innovation in architectural design. Therefore, it is very necessary to focus on developing students’ right brain function. In this context, this study adds the development content of right-brain function to the architectural teaching program, and then selects the students in the architecture department of four colleges as the objects of research for one semester training, using “decomposition and combination training + associative ability training”, “decomposition and combination training”, “associative ability training”, and “General course teaching”. During the experiments, students’ architectural design levels and brain endorphin secretion were recorded and analysed. The results showed that the creativity and aesthetics of the first three groups of students’ architectural design had been greatly improved, and the content of brain endorphins was significantly higher in the architectural design than the fourth group of students. This shows that the first three groups of students have stronger ability to mobilize the right brain during the architectural design. In addition, the combination of “decomposition and combination training + associative ability training” is better than any method alone. This fully proves the significance of focusing on the development of right brain function in architectural teaching.