With the development of multimedia technology networks, information technology is rapidly changing the production, work and lifestyle of human society. This change has also brought important influence to education. E-learning is an emerging product under this. At the same time, English reading is a very important part in college English teaching. E-learning plays a very important role in college English reading teaching in the new era. This paper will study this phenomenon, starting from the development of E-learning and its application in college English reading education, and propose a reasonable teaching method for the current English reading teaching mode and E-learning structure. Questionnaires and other methods have verified their effectiveness, pointing out the direction for further research.