With the development of network information in China, the application scope of “Internet +” is more and more extensive. For China’s higher education, the Internet is also playing a significant role. From the network literature to the current network teaching, the Internet has affected the way of college students to receive education in various ways. Therefore, with the development of network, does the Internet exert a significant impact on the quality of China’ higher education? This paper conducts an empirical analysis of the impact of Internet development on the quality of China’s higher education from 31 provincial-level data from 2010 to 2016. The research results show that the Internet development has a significant role in promoting the quality of higher education. In the regional analysis, it is found that the Internet effect in central and western regions is higher than that in eastern regions. The regional differences show that the Internet is more effective in improving the quality of higher education in economic backward areas and narrowing the regional differences of education level.