When college students majoring in beauty are admitted with low Intrinsic Motivation, Course Satisfaction and Career Decision-Making are frequently lowered. To solve this problem, this study aimed to investigate how intrinsic motivation affects Course satisfaction and career decision-making efficacy in 4-year college students majoring in Beauty Health in Gangwon-do and the metropolitan area. The survey was conducted during November 11 to 20 in 2018, and 253 students participated. SPSS 21.0 software was used to analyse the data. The results revealed that factors of intrinsic motivation such as enjoyment effort and competence made a meaningful effect on awareness satisfaction, future planning, and job information among factors of course satisfaction. Other factors of intrinsic motivation such as competence, strain, and enjoyment effort were found to have a meaningful effect on problem solving and goal selection among factors of career decision-making efficacy. Considering the above results, it was concluded that when students in beauty major experience an increased intrinsic motivation, they become more satisfied with the course and their increased intrinsic motivation had a higher effect on their career and job decision making process. This implicates that their course satisfaction and career decision-making efficacy should be improved when the classes are designed to improve their intrinsic motivation rather than applying the standardized teaching methods.